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The significantMirnas() and significantGenes() functions access the significant features contained in the mirnaDE or geneDE slots of a MirnaExperiment object, and can be used to obtain the IDs of statistically differentially expressed miRNAs and genes.

Usage

significantMirnas(object)

significantGenes(object)

Arguments

object

A MirnaExperiment object containing miRNA and gene data

Value

A character vector of miRNA IDs (e.g. 'hsa-miR-16-5p', hsa-miR-29a-3p'...), or acharacter vector of gene symbols (e.g. 'TP53', 'FOXP2', 'TIGAR', CASP1'...).

Functions

  • significantMirnas(): Get the IDs of differentially expressed miRNAs

  • significantGenes(): Get the IDs of differentially expressed genes

Author

Jacopo Ronchi, jacopo.ronchi@unimib.it

Examples

# load example MirnaExperiment object
obj <- loadExamples()

# extract significant DE-miRNAs
sigMirnas <- significantMirnas(obj)

# extract significant DEGs
sigGenes <- significantGenes(obj)