This dataset contains a gene expression matrix resulting from a miRNA-Seq analysis of thyroid cancer. Specifically, these data originate from Riesco-Eizaguirre et al (2015), where they sequenced 8 papillary thyroid carcinomas (PTC) together with paired samples of normal thyroid tissue. The same thing was done for mRNAs in order to investigate the effects on target genes. Data included in this package have been obtained through the Gene Expression Omnibus (GEO accession: GSE63511).
Usage
data(mirnaCounts)References
Garcilaso Riesco-Eizaguirre et al., “The MiR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis,” Cancer Research 75, no. 19 (September 30, 2015): 4119–30, https://doi.org/10.1158/0008-5472.CAN-14-3547.